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CAS No.4728-12-5 | (2,2-Dimethyl-1,3-dioxan-5-yl)methanol

CAS No.4728-12-5 | (2,2-Dimethyl-1,3-dioxan-5-yl)methanol

Name: (2,2-Dimethyl-1,3-dioxan-5-yl)methanol CAS No.4728-12-5 MF: C7H14O3 MW: 146.18 Purity:97% Package: 5g,25g,100g,500g,1kg,25kg Worldwide Delivery

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Analytical Chemicals

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Product introduction

Introduction and application of CAS No.4728-12-5 | (2,2-Dimethyl-1,3-dioxan-5-yl)methanol

(2,2-Dimethyl-1,3-dioxan-5-yl)methanol is a nucleotide that is structurally related to 2-amino-6-chloropurine. It has been shown to inhibit the incorporation of uracil into dsDNA and to act as a competitive inhibitor of adefovir and bisphosphonates. (2,2-Dimethyl-1,3-dioxan-5-yl)methanol inhibits phosphorylation by methylation of the hydroxyl group on the C5 position of the sugar moiety. This reaction results in an alkylated sugar with a phosphite group at the C5 position. The resulting product can undergo chloromethylation, which generates an additional reactive site for covalent modifications such as acetalization or esterification.

Synonyms:

2,2-Dimethyl-5-(hydroxymethyl)-1,3-dixoane;
(2,2-Dimethyl-1,3-dioxan-5-yl);
2,2-Dimethyl-5-(hydroxymethyl)-1,3-dixoane;
5-HydroxyMethyl-2,2-diMethyl-1,3-dioxane;
1,3-Dioxane-5-Methanol,2,2-diMethyl-;
(2,2-Dimethyl-1,3-dioxan-5-yl)methanol

Specification of CAS No.4728-12-5 | (2,2-Dimethyl-1,3-dioxan-5-yl)methanol

CAS No.	4728-12-5
MF	C7H14O3
MW	146.18
Melting point	197-198℃
Boiling point	208℃
Density（25℃，g/cm3）	1.004
acidity coefficient(pKa)	14.58±0.10(Predicted)